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List of Treatments for Hyperhidrosis

See what members are saying about hyperhidrosis treatments, the side effects to expect, and the drug basics.

All treatment information is medically reviewed · September 23, 2025

Oxybutynin

Overview
Oxybutynin is a prescription drug approved by the Food and Drug Administration (FDA) to treat overactive bladder. Oxybutynin may be prescribed off-label to treat certain types of excessive sweating including…

Prescription antiperspirants

Overview
Antiperspirants are the first line of treatment for hyperhidrosis. Antiperspirants with the maximum concentrations of active ingredients are available only with a prescription. Prescription antiperspirant brands…

Propantheline

Overview
Propantheline is a prescription drug approved by the Food and Drug Administration (FDA) to treat stomach ulcers. Propantheline may be prescribed off-label to treat certain types of excessive sweating including…

Qbrexza (Glycopyrronium)

Overview
Qbrexza is approved by the U.S. Food and Drug Administration (FDA) for the topical treatment of primary axillary hyperhidrosis (excessive underarm sweating) in adults and children 9 years of age and older. It is…

Robinul (Glycopyrrolate)

Overview
Robinul is a prescription drug approved by the Food and Drug Administration (FDA) to treat stomach ulcers. Robinul may be prescribed off-label to treat certain types of excessive sweating including generalized…

Sofdra (Sofpironium)

Overview
Sofdra is approved by the U.S. Food and Drug Administration (FDA) for the treatment of primary axillary hyperhidrosis in adults and children 9 and up. Sofdra is also known by its drug name, sofpironium.

Sofdra is…

Sweat gland removal

Overview
During sweat gland excision surgery, sweat glands under the arms are surgically removed and/or damaged. Techniques for sweat gland excision include liposuction, curettage, lasers, and excision
Sweat gland…

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