I got botox injections in one of my palms to try it out, it was quiet painful as my doctor didnt use anything to numb the area and I chose to not be asleep while they did it. It cleared the area of sweat id say about 80% which was pretty good! However botox only lasted about 3 months for me before the sweating came back. A problem with getting botox in a place like your hands which I had is it weakens your muscles greatly in the area. For a few weeks I couldnt even open a toothpaste tube ! And my hand had bad bruising and the injection spots on it for about a week after getting it.

I received botox injections in both my hands. It was very painful and only work for a week. Not worth it for me at all.

Depends on what type hyperhydrosis you have bit if its primary on hands and armpits there is a surgery to cut the nerves to the sweat glands covered by ohip in ontario. Or there is miradry treatments which is basicly lazer sweat gland removal $1600 a treatment most ppl need 1-3treatments