Over-the-counter (OTC) antiperspirants for Hyperhidrosis | MyHyperhidrosisTeam

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Antiperspirants are the first line of treatment for hyperhidrosis. Some antiperspirants are available with higher-than-normal concentrations of active ingredients without a prescription. Most familiar brands of antiperspirant offer a “clinical strength” version that may be readily available in the personal care section at department stores or drugstores. Other brands, such as Certain Dri, Duradry, and ZeroSweat specialize in clinical strength, over-the-counter (OTC) antiperspirants.

The most common active ingredients of OTC antiperspirants are Aluminum zirconium tricholorohydrex and Aluminum chloride hexahydrate. Both ingredients work by forming temporary plugs at the opening of sweat ducts in the skin.

How do I take it?
When choosing a product, make sure that it is an antiperspirant and not a deodorant only. On their own, deodorants do not reduce sweating. Try products with lower concentrations of active ingredients first. If these do not work, choose stronger products next. Using the product with the lowest effective concentration will help minimize skin irritation.

Many people with hyperhidrosis find soft solid antiperspirant more effective than other formats. However, aerosol sprays can work well for feet. Other products are available in the form of roll-ons or pre-soaked, disposable wipes. Massaging the antiperspirant into the skin may increase its effectiveness.

Antiperspirants are applied topically to the underarms and other areas where excessive sweating is a problem. Most OTC antiperspirants work best when applied twice a day, in the morning and at night before bed. To minimize skin irritation, always apply antiperspirants to completely dry skin. Use a hair dryer on a low setting to dry the skin first, if necessary.

Side effects
Antiperspirants can cause a rash or skin irritation, especially when applied to wet or broken skin, or immediately after shaving. Antiperspirants may stain clothing.

People with advanced kidney disease should discuss antiperspirant use with their doctor.

For more details about this treatment, visit:

Antiperspirant Basics – International Hyperhidrosis Society

Antiperspirants – National Kidney Foundation

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