Glycopyrrolate is a prescription drug approved by the Food and Drug Administration (FDA) to treat conditions including peptic ulcers and excessive drooling. Glycopyrrolate may be prescribed off-label to treat certain types of excessive sweating including generalized hyperhidrosis and cranio-facial hyperhidrosis in people who have not found relief from other treatments. Glycopyrrolate may be used on an as-needed basis to temporarily stop sweating during special events. Glycopyrrolate is available as a generic drug and also sold under brand names including Robinul and Cuvposa.
Glycopyrrolate is an anticholinergic. Glycopyrrolate is believed to work by blocking chemical messengers that trigger the sweat glands to produce sweat.
How do I take it?
Take Glycopyrrolate as prescribed by your doctor.
Glycopyrrolate comes in tablet and oral solution forms.
FDA-approved labels for Glycopyrrolate lists common side effects including headaches, dry mouth, changes in the sense of taste, nasal congestion, flushing, drowsiness, dizziness, insomnia, nervousness, vision changes, tachycardia (fast heartbeat), heart palpitations, nausea, vomiting, constipation, bloating, urine retention, and impotence.
Rare but serious side effects listed for Glycopyrrolate include intestinal obstruction and increased risk for heat prostration (fever and heatstroke).
Recent studies indicate that people 65 or older using anticholinergic drugs long-term may be at increased risk for developing dementia or brain atrophy.
For more details about this treatment, visit:
Robinul – RxList
Cuvposa – Merz Pharmaceuticals
Medications – International Hyperhidrosis Society